19 results
Paths to Defective Homologous Recombination DNA Repair in Breast Cancer. Each individual mutation or epigenetic aberration
DNA Repair in Breast ... common feature of breast ... cancer #Pathophys #Honc ... BreastCancer #DNARepair #NEJM
Radiation-Induced Angiosarcoma after Breast-Cancer Treatment - Physical examination revealed an area of skin 10 cm in
Angiosarcoma after Breast-Cancer ... the dermis and breast ... Clinical #Derm #Honc ... #Angiosarcoma #Breast ... Radiation #Microscopy #NEJM
Fournier’s Gangrene - Physical examination was notable for necrotic-appearing tissue in the scrotum and perineum, with
perineum, with areas ... Clinical #Surgery #CT ... #Subcutaneous #NEJM
Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer - Progression-free Survival in the Intention-to-Treat Population.
III Non–Small-Cell ... the Intention-to-Treat ... #EBM #Honc #PACIFIC ... Durvalumab #NSCLC #NEJM
Melanoma of the Foot - The physical examination revealed a well-defined, fleshy, reddish plaque measuring 2
examination revealed a well-defined ... surface and black areas ... Derm #Podiatry #Honc ... Melanoma #Foot #NEJM
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... - gastric and breast ... Chest CT: • Ground-glass ... IgG level X2 at least
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
hyperkeratotic central areas ... #clinical #photo ... #NEJM #tinea #capitis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
occur when the CD4-cell ... less than 200 cells ... recovery (CD4-cell ... enhancement on CT ... periventricular areas
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
• Bronchial breath ... Total white blood cell ... Uremia (blood urea ... count < 4,000 cells ... radiograph or CT
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... that were in his breast ... #NEJM #clinical ... #radiology #CT # ... squamous #cell #