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diagnosis differential management syndrome cancer causes hypokalemia incomplete kawasaki oncology pathophysiology peds rhabdomyolysis treatment workup
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... tubule (DCT) Clinical ... Hypocalciuria (spot urine ... • Autoimmune disease ... Syndrome #diagnosis #nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Gitelman Syndrome ... Elevated Renin Urine ... excretion of Cl > 0.5% Clinical ... dominant kidney disease ... Diagnosis #Workup #nephrology
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... if they have no clinical ... 15,000/mm3, and urine ... Diagnosis #Peds #Pediatrics ... #Kawasaki #Disease
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Dermatomyositis Clinical ... Weakness - Dark urine ... Hyperuricemia • Hyponatremia ... of underlying disease ... causes #treatment #nephrology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... 100 mOsm/kg = Urine ... amyloidosis) • Liver disease ... #nephrology #oncology
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