16 results
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Causes of Metabolic ... Alkalosis - Differential ... Diagnosis Algorithm ... Urine chloride ... , Gitelman's Syndrome
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... , Gitelman syndrome ... Urine chloride is ... #urine #Algorithm ... #nephrology #differential
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... • Urine Chloride ... • Urine Ca/Cr ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Alkalosis - Differential ... Diagnosis Algorithm ... , Gitelman Syndrome ... #nephrology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Metabolic Alkalosis ... Differential Diagnosis Algorithm ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... #Diagnosis #Algorithm
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Alkalosis - Differential ... Diagnosis Algorithm ... , Gitelman Syndrome ... #Nephrology #Causes
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... volume contracted: urine ... volume expanded: urine ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... → Hypokalemia Metabolic ... alkalosis - ... #nephrology #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... alkalosis • Normal ... (spot urine, calcium-creatinine ... Rhabdomyolysis Treatment ... #nephrology #management
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
Gas) (-) Likely Metabolic ... Alkalosis Urine ... Barter, or Gitelman ... Syndrome Unremarkable ... #alkalosis #algorithm