43 results
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
A table of lab ... additions, for diagnosing ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #Neonatology #Peds ... #Pediatrics #Table
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
the lab values table ... #Diagnosis #Algorithm ... #Differential # ... Neonatology #Peds ... #Pediatrics #Table
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... Diagnosis of MALA ... presentation - Clinical ... presentation also ... includes symptoms
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... heavy metals), Critical ... Malnutrition, Metabolic ... Weakness #Causes #differential ... #diagnosis #neurology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
complications such as ... A urine K/Cr ratio ... #Hypokalemia #diagnosis ... #Algorithm #differential ... #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Heat stroke - Metabolic ... Dermatomyositis Clinical ... causes #treatment #nephrology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
free fatty acid metabolism ... postpartum): • Initial symptoms ... Findings: • ↑AST/ALT ... infiltration) Differential ... Diagnosis: Viral
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... , Heat stroke, Metabolic ... Dermatomyositis) AKI - Pathophysiology ... hour with goal urine
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... • This is also ... Signs/Symptoms/Complications ... non-arousable, decr urine ... endocrinology #peds
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
common, there are also ... and decreased metabolism ... Reye syndrome (Peds ... Hyperammonemia #Differential ... #Diagnosis