6 results
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Urine Na+K / serum ... or Ineffective (UNa ... differential #diagnosis #table
Hyponatremia - Diagnostic Evaluation Algorithm

Step 1: Consider whether Posm may actually be normal or elevated
Step 2:
Evaluation Algorithm ... Check Uosm and/or Urine ... status and measure UNa ... tests Step 5: If SIADH ... considered likely, the cause
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
electrolyte abnormality caused ... among the possible causes ... Another important physiological ... Measured urine sodium ... EBV #potomania #SIADH
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... promoting passive sodium ... Saline: • If Urine ... osmolality < 538 AND UNa ... #Management #hyponatremia
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
administered • This can cause ... promoting passive sodium ... 0.9% NS • If Urine ... osmolality < 538 AND UNa ... #Management #hyponatremia
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... 100 mOsm/kg = Urine ... inappropriate • SIAD ... chemotherapy, nausea