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Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Hyperphosphatemia • Hyperkalemia ... renal failure • Hypocalcemia ... Vomiting, decreased urine ... coma SIADH: • Hyponatremia ... differential #diagnosis #cancer
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... : SIADH, Renal Sodium ... Present (Uosm ≥100): Hypovolemia ... diagnosis #table #sodium
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... and urine osmolality ... Measured urine sodium ... #RAAS #Hypovolemia ... #EBV #potomania
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... in Cancer UOsm ... 100 mOsm/kg = Urine ... appropriate • Hypovolemia