10 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Utilizing Uric Acid ADH ... 2) Urine Osmolarity ... 3) Urine Sodium ... Low Uric Acid → SIADH
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
, urine sodium concentration ... and urine osmolality ... helps to differentiate ... Measured urine sodium ... #hyponatremia #ADH
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... treat underlying cause ... Pulmonary Diseases ... , SSRIs) - SIADH ... diagnosis #nephrology #sodium
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... 3 questions to work ... Measure urine osmolality ... volume status (EABV ... management #nephrology #sodium
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Hyponatremia - Differential ... secretion (SIADH ... hemorrhage) - Pulmonary ... Diagnosis #Table #Causes ... #Sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... volume-based algorithm Urine ... restriction alone in SIADH ... , Renal Sodium loss ... #differential #
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
promoting passive sodium ... Saline: • If Urine ... osmolality < 538 ... antagonists: • Blocks ADH ... #Management #hyponatremia
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
promoting passive sodium ... 0.9% NS • If Urine ... osmolality < 538 ... vaptans) • Blocks ADH ... #Management #hyponatremia
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
with suppressed ADH ... diabetes insipidus Differential ... Pseudohyponatremia, SIADH ... intoxication Initial Workup ... , Urine Sodium
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... 100 mOsm/kg = Urine ... inappropriate • SIAD ... chemotherapy, nausea ... algorithm #nephrology #oncology