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diagnosis dermatology differential management blood product reactions antimda5 antimda5dm antinxp2 antinxp2dm autoimmune comparison erythemas erythematosus joint lupus myopathy myositis pain
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Seborrhea • Dermatomyositis ... Heliotrope • Dermatomyositis ... differential #diagnosis #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... ulcerations • Skin ... 50% of cases • Skin ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis #Rheumatology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
Summarized Erythema ab ... centrifugum • A chronic skin ... Usually composed ... differential #diagnosis #dermatology ... #compared
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
have typical DM skin ... (blue-purple) rash ... • Erythematous rash ... ulcerations • Skin ... diagnosis #management #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
antigens (often ABO ... maculopapular rash ... anti-HLA or anti-HNA Ab ... infections with skin ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
antigens (often ABO ... maculopapular rash ... anti-HLA or anti-HNA Ab ... infections with skin ... diagnosis #management #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... Anti-Synthetase Ab ... Myositis #Myopathy #rheumatology
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