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diagnosis algorithm causes pulmonary rheumatology vasculitis acute aki renal antigbm basement classification comparison disease diseases giomeruiar glomerular injury kidney kidneyinjury
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Henoch-SchonIein Purpura Anti-GBM ... Limited to Kidney: Anti-GBM ... pulmonary involvement: Anti-GBM ... Disease (Goodpasture's ... #Vasculitis #differential
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... polyangiitis, Microscopic ... Basement Membrane: Goodpasture's ... ab, anti-GBM ab ... #diagnosis #nephrology
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Glomerulonephritis ... - Differential ... Wegener's) • P-ANCA: Microscopic ... Churg Strauss) Anti-GBM ... diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... membrane: Goodpasture ... renal failure (glomerulonephritis ... ANCA antibody, Anti-GBM ... usually low in anti-GBM
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Membrane Disease (Goodpasture's ... rapidly progressive glomerulonephritis ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... AntiGBM #diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... • Lupus ISN/RPS ... Amyloid RPGN • Anti-GBM ... glomerular #diseases #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... and signs • Glomerulonephritis ... Vasculits: ANCA, ANA, Anti-GBM ... , Anti-ds-DNA, C3 ... #Diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - Differential ... Rapidly Progressive Glomerulonephritis ... • Anti-GBM antibodies ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... -ANCA): • Microscopic ... ) • Anti-GBM - ... Urticarial Vasculitis (anti-C1q ... Dx: GPA, EGPA, microscopic
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... -ANCA)): Microscopic ... abdominal pain and GN Anti-GBM ... #Vasculitis #Differential
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