13 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Liver Injury (DILI ... Calculate R-Value ... gastroenterology #algorithm
Heparin-Induced Thrombocytopenia (HIT) Evaluation Algorithm

- Dr. Josh Farkas @PulmCrit

#4TScore #HITT #Algorithm #HeparinInduced #Thrombocytopenia #Diagnosis #Criteria #Hematology
Heparin-Induced ... Thrombocytopenia ... (HIT) Evaluation ... #Diagnosis #Criteria ... #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis ... Algorithm DILI ... non-essential drug/HDS treatments ... #Algorithm #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... effect following treatment ... following EtOH induced ... thrombocytopenia
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
abnormality vs bone Bili ... ALP ≥ 2x ULN R Value ... Hospital of Baltimore IM ... Transaminitis #diagnosis ... #hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... treatment of Hereditary ... elevated iron indices ... and hematologic
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and to adjust treatment ... #Hematology #HIT ... #Heparin #Induced ... #Thrombocytopenia ... #Algorithm
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... constitutional symptoms • Treatment ... life-threatening • Treatment ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology