36 results
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
- Pathophysiology ... New-onset fever with rash ... #Diagnosis #Dermatology ... #Rash #Maculopapular ... Targetoid #Algorithm #Differential
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... #Diagnosis #Dermatology ... #Rash #Erythroderma ... Nikolsky #Algorithm #Differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... Lysis Syndrome: • Pathophysiology ... sudden death • Lab values ... diagnosis #management #hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Pathophysiology: ... #Diagnosis #Dermatology ... #Rash #Petechiae ... Palpable #Algorithm #Differential
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
plugging -> Discoid Rash ... Malar (butterfly) Rash ... Manifestations #pathophysiology ... diagnosis #signs #symptoms ... #complications
Etiology and Complications of Cirrhosis

#Causes #Complications #Cirrhosis #Differential #Pathophysiology #Hepatology
Etiology and Complications ... Cirrhosis #Causes #Complications ... #Cirrhosis #Differential ... #Pathophysiology ... #Hepatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... fraction < 20% Differential ... , Schnitzler) Complications ... management #treatment #rheumatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... (aPL) 30-45% Differential ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology