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hepatology transaminitis algorithm injury management causes enzymes hepatocellular workup abnormal aflp arterial biliary chemistry cholangitis cholestatic cirrhosis classification dehydrogenase dili
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... Chronic Viral Hepatitis ... #Differential # ... Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... #Injury #hepatology ... #LFTs #transaminitis ... #differential # ... diagnosis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... Transaminitis #diagnosis ... #differential # ... hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... Infections: Hepatitis ... #Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... or symptoms of ... Calculate R-Value ... Idiosyncratic #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Alcoholic hepatitis ... • Others #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... #chemistry #diagnosis ... #differential # ... #LFTs #RValue #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Diagnosis: Viral ... Hepatitis, Preeclampsia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... pylori test (GI symptoms ... gastric bypass), LFT ... (liver disease)
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential # ... Diagnosis
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