47 results
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... • Tumor lysis syndrome ... glycosides • High acute ... blockers - MCW Nephrology ... MCW_Nephrology #HyperKalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... starts by measuring ... , Gitelman's syndrome ... #hypokalemia ... algorithm #causes #nephrology
Acute Hyperkalemia Management
 • Membrane Stabilization: Calcium Gluconate (10%), Hypertonic (3%) Normal Saline
 • Shifters: Insulin
Acute Hyperkalemia ... Management • Membrane ... Shifters: Insulin (Short ... Bicarbonate, Sodium ... #Hyperkalemia #
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... overdose) - Sodium ... renal Fanconi syndrome ... differential #diagnosis #nephrology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... 90 minutes) • Sodium ... LouLectures #Hyperkalemia ... #management #potassium ... #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... Hypocalciuria (spot ... #diagnosis #nephrology ... #management #pathophysiology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Diagnosis Algorithm Hypovolemia ... Hypovolemia, UNa ... Stress, Drugs, Syndrome ... UNa > 20: • Acute ... Algorithm #Causes #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Algorithm #diagnosis #sodium ... #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
diuresis, Bartter's syndrome ... use), Gitelman's syndrome ... excess and related syndromes ... Hypomagnesemia, Acute ... differential #diagnosis #nephrology