28 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... ATRA treatment Pathophysiology ... initiation • Differential ... #management #hematology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Hypokalemia - Differential ... K-ATPase which imports ... - Refeeding Syndrome ... #Hypokalemia #Differential ... potassium #low #pathophysiology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... hyperleukocytosis (AML ... Hyperviscosity #Syndrome ... #Causes #Differential ... Diagnosis #Treatment #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... : • Pathophysiology ... sudden death • Lab values ... TLS #diagnosis #management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Abdominal compartment syndrome ... Sophia_Hayes_MD #Shock #Differential ... #Diagnosis #criticalcare ... algorithm #treatment #management
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
myeloma, CML, AML ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... • Nephrotic Syndrome ... from prosthetic valves ... Infected cardiac valves ... Venous #Arterial #pathophysiology
Mask Oxygen Delivery Devices

Simple Mask aka Hudson's Mask:
 • Flow 6-10 LPM
 • FiO2 35-50%
Face Tent:
The venturi valves ... have two one-way valves ... the exhalation ports ... Delivery #Devices #management ... #pulmonary #criticalcare
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... iniury, Compartment syndrome ... Dermatomyositis) AKI - Pathophysiology ... #Diagnosis #Management
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
myocarditis, etc), Valves ... CCB, BB, BRASH syndrome ... cytokine release syndrome ... Shock #diagnosis #differential ... guyton #curves #criticalcare