16 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... symptoms of liver disease ... Calculate R-Value ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... Diagnosis Algorithm ... Alcohol-related liver disease ... #Diagnosis #Algorithm ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... extrahepatic source - Tests ... #differential #diagnosis ... #algorithm #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... abnormality vs bone Bili ... ALP ≥ 2x ULN R Value ... Transaminitis #diagnosis ... #hepatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... Test for the respective ... biopsy • Lab values ... supporting hematologic ... #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... → liver test abnormalities ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... #hepatology #algorithm
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... LFTs) - Normal Values ... hepatocellular injury ... Interpretation #diagnosis ... #hepatology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
and Workup Summary ... Criteria - Recurrent abdominal ... cultures, but test ... Rule out celiac disease ... Balloon Expulsion Test
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... of cholestatic disease ... Alcoholic liver disease ... liver #chemistry #diagnosis ... #differential #Hepatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
to local skin injury ... Positive pathergy test ... is a skin prick test ... • Nonsurgical abdominal ... signs #symptoms #rheumatology