23 results
Approach to the Hospitalized Patient with Cirrhosis
1) Recognize and Manage Decompensation
 • Ascites
 • Variceal Bleeding
Decompensation • Ascites ... • Variceal Bleeding ... • Hepatic Encephalopathy ... • Hepatorenal Syndrome ... #diagnosis #treatment
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Disease (Cirrhosis ... Complications • Ascites ... Esophageal Varices • Hepatic ... Hepatopulmonary Syndrome ... • Hepatorenal Syndrom
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
of portal HTN: ascites ... and hepatorenal syndrome ... Clues to non-cirrhotic ... portal HTN: • Ascites ... sarcoidosis) • Liver
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... - Budd-Chiari syndrome ... Liver disease ... - Cirrhosis ... #Causes #diagnosis
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... Hypertension - Hepatic ... : • Cirrhosis ... disease • Acute liver ... Hypertension - Post-Hepatic
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... Fitz-Hugh-Curtis syndrome ... Disease, Fulminant Hepatic
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... or secondary to cirrhosis ... 3) Sinusoidal: Cirrhosis ... , Polycystic liver ... post-sinusoidal: Budd-Chiari syndrome
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... of ascites removed ... • Hepatorenal syndrome ... Indications #Management #Cirrhosis ... #treatment #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
>1.1 g/dl): - Cirrhosis ... - Massive liver ... - Fulminant hepatic ... failure - Hepatic ... without cirrhosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ... presentation: Hepatic ... disorder (e.g. ascites