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diagnosis hematology oncology product reactions anemia chronic cll dermatologic differential gpa granulomatosis leukemia lymphocytic mds myelodysplasia myelodysplastic nonpalpable palpable polyangiitis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... meningitidis - Varicella ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... resemble pyoderma gangrenosum ... • Goodpasture syndrome ... vasculitis (inflamed blood ... rash #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... just beneath the skin ... Causes • Anemia • Aplastic ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... Pure red cell aplasia ... • Richter’s Syndrome ... workup #oncology #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... due to marrow aplasia ... infections with skin ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... due to marrow aplasia ... infections with skin ... Transfusion #diagnosis #management ... #hematology #reactions
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