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chronic lymphocytic causes classification differential disorders generalized hemeonc hemophagocytic hodgkins lymphohistiocytosis lymphoma lymphoproliferative post ptld rheumatology summary transplant transplantation treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... lymphoid organs When Cancer ... • Lymphadenopathy ... #Hematology #Oncology ... #Diagnosis
Differential Diagnosis for Generalized Lymphadenopathy Viral • HIV • EBV • CMV • HBV • Dengue • Rubella
• Lymphoma • Leukemia ... • Metastatic cancer ... Amyloidosis • HLH ... #Causes #Algorithm ... #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... Exam/Signs: • Lymphadenopathy ... Diagnosis: • ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... ) Asymptomatic lymphadenopathy ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... lymphoma, B-cell ... B-LNH), solid cancers ... #management #treatment ... #summary #rheumatology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
cancers in recipients ... haploidentical>unrelated>HLA ... symptoms, unexplained hematologic ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Presentation: • Lymphadenopathy ... lymph node biopsy (diagnostic ... classification #hematology ... #oncology #management
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