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diagnosis hematology oncology management aids cell chronic cll cns differential hemophagocytic hiv hlh hodgkins infections infectiousdiseases leukemia lymphocytic lymphohistiocytosis neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... and petechiae Causes ... anemia Treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... Weight loss • Anemia ... ) Classification ... Workup: • Full ... Treatment • Early
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Neutropenia, anemia ... Pure red cell aplasia ... microglobulin Treatment ... Leukemia #diagnosis #workup
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Infections+++: Virus ... , B-cell lymphoma ... Treatment: • ... inhibitors under evaluation
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
and primary CNS lymphoma ... should be based on clinical ... presentation, temporal evolution ... Antimicrobial treatment ... Demyelinating disease caused
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... • No CRAB - no anemia ... Diagnostic Evaluation ... Bone marrow Treatment ... • Non-Hodgkin Lymphoma
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