12 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • Epstein-Barr virus ... Treatment: ... hematology #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... Usual therapeutic management ... Lupusreference #druginduced
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... COVID 19 - Zika virus ... Guillain-Barre Clinical ... Syndrome #diagnosis #management ... #treatment #neurology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
are excellent at evaluating ... the determined cause ... #differential #algorithm ... #heartfailure #chf ... #criticalcare #
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... intrinsic factor, IF) Clinical ... total body stores Evaluation ... Check for IF ab Treatment ... Deficiency #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... and cauda equina TREATMENT ... specific therapy, the clinician ... Syndrome #diagnosis #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based on clinical ... presentation, temporal evolution ... present in 15% of cases ... Antimicrobial treatment ... Demyelinating disease caused
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... zoster, West Nile virus ... Herpes simplex virus ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... and pernicious anemia ... Clinical Manifestations ... #treatment #neurology