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diagnosis treatment algorithm causes rhabdomyolysis hyponatremia kidney potassium alkalosis blood cardiology chf chloride clinical criticalcare defects epithelial foamed heartfailure hematuria
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... Hypocalciuria (spot urine ... ratio 0.5%) Differential ... #nephrology #management
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... , Gitelman syndrome ... #hypokalemia ... #differential # ... algorithm #diagnosis #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
A urine K/Cr ratio ... • Diarrhea A urine ... , Gitelman syndrome ... diagnosis #Algorithm #differential ... #potassium #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
ascending limb Gitelman ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
, Gitelman syndrome ... sodium is typically ... the excretion of sodium ... #Algorithm #nephrology ... #differential #
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
volume-based algorithm Urine ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Weakness - Dark urine ... hour with goal urine ... causes #treatment #nephrology
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
(Goodpasture's syndrome ... Renal #Transplant #differential ... kidney #blood #urine ... #management #treatment ... #nephrology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
Hypertension - Differential ... (correction of hypokalemia ... Oral sodium loading ... test (with 24-h urine ... Screening #Workup #table
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Diagnosis and Management ... hour with goal urine ... per day until stable ... Dialysis for severe hyperkalemia
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