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hematology differential aplastic chronic clinical common cutaneous cvid fatigue hypogammaglobulinemia immunodeficiency immunology isolated mucormycosis neutropenia oncology skin variable
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... • Malignancy Infectious ... Hepatitis • HIV ... #Algorithm #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... and petechiae Causes ... Idiopathic • Infections ... #oncology #hematology ... #diagnosis #management
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Antineoplastic Viral Infection ... • Epstein-Barr Virus ... #Algorithm #Causes ... #Hematology
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Diagnosis? ... trauma, aplastic anemia ... Indiana University Infectious ... #dermatology #skin ... #clinical #photo
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... and M panel Management ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... #diagnosis #management
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