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differential hematology causes hemolytic aiha aplastic chronic disorders fatigue gap globulin management oncology platelet protein proteingap testing thrombocytopenia
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... - Extrinsic: Autoimmune ... Macroangiopathic, Infections ... #MCV #Algorithm ... #hematology
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Anemia (AIHA) ... - Secondary Infectious ... EBV, HCV, HEV ... #AIHA #Diagnosis ... #Differential #Algorithm
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
procedures - Infection ... , HCV - Alcohol ... /HCV testing - ... changes), high MCV ... anemia (vegan,
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... - HCV - HIV ... #oncology #hematology ... #diagnosis #management
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Hematologic • Anemia ... • Malignancy Infectious ... Epstein-Barr Virus ... Hepatitis • HIV ... Autoimmune / Inflammatory
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... inclusions - If infection ... elliptocytosis, autoimmune ... #Algorithm #workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Include: • Viral infections ... Cirrhosis, ETOH, autoimmune ... Thalassemia, Sickle cell anemia ... #differential #diagnosis
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