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diagnosis management blood reactions activation agglutinin aplastic cold common cvid differential disease hemolytic hypogammaglobulinemia immunodeficiency immunology macrophage mas nonpalpable oncology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... - Hemolytic anemia ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... immunodeficiency virus ... • Epstein-Barr virus ... #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... • Symptoms of anemia ... Mycoplasma, EBV, HIV ... #hematology #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Diagnosis #Management #Hematology ... #Rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
risk secondary ... disease • Infectious ... autoimmune hemolytic anemia ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... • Infection - ... Infection occurs ... likely to cause infections ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Blood products contain ... of transfused products ... Infection - Infection ... diagnosis #management #hematology
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