12 results
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
- Differential Diagnosis ... Neoplastic / Hematologic ... Epstein-Barr Virus ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Antiparkinsonian agents are diagnostic ... tremor ("rabbit syndrome ... months or years of treatment ... #SideEffects #pharmacology ... #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
fatal • Causes: Drugs ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Criteria for Diagnosis ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... anaphylaxis (→ 3-1) Drug ... • Serotonin syndrome ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... immune deficiency, Drugs ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
life-threatening • Treatment ... Usual therapeutic management ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... superinfection, drug ... : • Drug reaction ... #Inflammatory #Syndrome ... #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... ) • Sepsis • Drug-induced ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology