13 results
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Lactulose: Mechanism ... Lactulose → ↑ Lactic Acid ... , Acetic Acid → ... #Lactulose #pharmacology ... #hepatology #pathophysiology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulants #Medications ... #Pharmacology # ... Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... ↓ Hepatic Bile Acid ... ↑ Hepatic Bile Acid ... sequestration #pathophysiology ... #pharmacology #
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: ... Mechanism of Action ... analog of the amino acid ... #pathophysiology ... #hematology #TXA
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Mechanism of Action ... Common Diabetes Medications ... #Diabetes #Medications ... #pharmacology # ... pathophysiology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
chronic hepatitis C virus ... treatment #hcv #medications ... infectiousdisease #hepatology ... HepatitisC #Management #Pharmacology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... • Indications: ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology ... #indications #dosing
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... Pharmacology Pharmacokinetics ... TXA #Tranexamic #Acid ... #Indications #Pharmacology ... #hematology
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
Uric Acid Homeostasis ... metabolized to uric acid ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications