10 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... The underlying pathophysiology ... of the crisis ( ... Parvovirus B 19, a virus ... #Features #Signs
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
• Salt wasting crisis ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Kernig's Sign in Meningitis

Kernig's sign is present if the patient, in the supine position with the
Kernig's Sign in ... Meningitis Kernig's sign ... video, the infant cries ... PhysicalExam #Pediatrics #Peds ... #neurology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Respiratory syncytial virus ... #OtitisMedia #pathophysiology ... diagnosis #symptoms #signs ... #peds #pediatrics
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
muscles: “myasthenic crises ... test - Cogan sign ... - Peek sign ... Myasthenia Crises ... immunosuppressants - Meds
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
infection that cross-reacts ... , Epstein-Barr virus ... HIV), and Zika virus ... the underlying pathophysiology ... diagnosis #management #neurology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
• Mutism Pathophysiology ... • Examine for signs ... Arms extended; wrists ... from the body; wrists ... #PhysicalExam #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Hypertensive crisis ... Etiology: • Pathophysiology ... Seizures: Treat with AEDs ... diagnosis #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... than 2/3 of the cross-sectional ... Herpes simplex virus ... diagnosis #management #neurology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Scleroderma Renal Crisis ... Scleroderma Renal Crisis ... anemia (MAHA) Pathophysiology ... , add other BP meds ... #rheumatology #nephrology