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neurology syndrome myasthenia rheumatology treatment algorithm aplastic barre bee cardiology chronic effusions endocarditis fatigue guillain guillainbarre hematology immune infections infectiousdiseases
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... - Differential ... Hematologic • Anemia ... Hepatitis • HIV ... • Myasthenia Gravis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... myasthenia Diagnosis ... stimulation - Single fiber ... immunologic assay - MuSK ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... - HCV - HIV ... oncology #hematology #diagnosis ... #management
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential ... Diagnosis Framework ... #differential # ... diagnosis #msk #
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... : • Based on clinical ... More likely to cause ... #Myasthenia #Gravis ... #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... , HIV, Hep A/B/CMV ... #management #neurology ... #differential
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... MRI lesions and clinical ... consistent with MS ... noninflammatory #differential ... #diagnosis
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
nodes • Roth’s spots ... Septic Emboli Cause ... Marantic (NTBE) Differential ... Leukocytosis, anemia ... #management #cardiology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... COVID 19 - Zika virus ... Guillain-Barre Clinical ... • Weakness: Starts ... #management #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... system: small-fiber ... phenomenon (16%) MSK ... #Management
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