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diagnosis sle management systemic differential classification comparison table vasculitis cerebritis clues cns cryoglobulinemia cryoglobulins dil drugs medications neurology pharmacology presentation
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... autoantibodies that will cause ... Puncture, EEG Treatment ... #Erythematosus ... CNS #neurology #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Systemic #Erythematosus ... Management #Summary #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, macular, patchy ... Non-autoimmune rheumatologic ... • Asymptomatic pericarditis ... endocarditis • Valvular ... #Diagnosis #Rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... 4) Always with pericarditis ... sometimes « viral pericarditis ... #system #erythematosus ... #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
or pericarditis ... associated with rheumatologic ... presentation of systemic lupus ... erythematosus. ... life-threatening causes
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 Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Erythematosus ( ... life-threatening • Treatment ... Lupusreference #druginduced ... #table #rheumatology
Causes of Acute Pericarditis: Infectious; Viral: Adenovirus Coxsackie virus A and B Echovirus Epstein-Barr virus Hepatitis Human immunodeficiency
Causes of Acute ... Posttraumatic Collagen vascular ... syndrome Systemic lupus ... erythematosus ... Rheumatic fever #Causes
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 Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Induced Systemic Lupus ... Erythematosus ... for 1 year of treatment ... Lupusreference #DrugInduced ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Vascular Sludging ... (e.g. systemic lupus ... erythematosus ( ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... erythematosus, ... differential #diagnosis #rheumatology
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