4 results
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Culture-Negative Infective Endocarditis ... See charts - ... antiphospholipid syndrome ... special stains (e.g ... valve tissue - Valvular
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Autoimmune (SLE ... nodes • Roth’s spots ... insult due to vascular ... ↑ ESR, CRP • EKG ... diagnosis #management #cardiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
• Autoimmune (SLE ... nodes • Roth’s spots ... Cholesterol emboli syndrome ... ↑ ESR, CRP • EKG ... Differential #Diagnosis #cardiology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... • Malignancy (e.g ... Endocrine disorders (e.g ... • Malar rash - spares ... • Libman-Sacks endocarditis