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diagnosis hemolytic autoimmune bandemia causes cbc cold disease erythematosus extravascular hemolysis intravascular lupus neutrophil pathophysiology rheumatology sle systemic wbc
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
(AIHA) - Differential ... Diagnosis Table ... hemoglobinuria) • Cold Agglutinin ... #AIHA #Differential ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... Infection Clinical ... • Symptoms of anemia ... younger pts) Differential ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
- Autoimmune (AIHA ... . primary cold agglutin ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... 9343(12)00450-0/abstract ... likelihood of negative clinical ... #differential # ... neutrophil #WBC #CBC #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... : • AIHA 10% • ... lymphopenia, low PLT • Anemia
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