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diagnosis oncology cppd differential approach calcium cll deposition dermatology druginduced hodgkins joint laboratory leukemia lupus lymphocytic lymphoma mds msk myelodysplasia
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
rheumatic fever • Chronic ... ), RA, crystal disease ... • Bloody: Trauma ... Joint #Pain #MSK #rheumatology ... #approach #workup
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... Chronic CPP Crystal ... Synovial Fluid: • WBCs ... • Metabolic syndrome ... #Comparison #rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
and Management ... sex • Metabolic syndrome ... frequent attacks • Arthritis ... Fluid Testing: • WBCs ... #treatment #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... synovial fluid • Gout ... urate crystals (gout ... Screening Tests for Chronic ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... pulses, bruis, or blood ... Large Vessel: Blood ... differential #diagnosis #rheumatology ... #classification
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Workup: • Complete ... #diagnosis #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Evolution: Chronic ... disease Dr. ... druginduced #lupus #sle #comparison ... #table #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... nonerosive inflammatory arthritis ... and lower jaw Treatment ... #Rheumatology # ... diagnosis #management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Synovial Fluid: • WBCs ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... #Rheumatology # ... diagnosis #management
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