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diagnosis oncology chronic leukemia agglutinin anemia arthritis classification cold common cvid fungal hemeonc hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology infections laboratory
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... Positive Coombs testing ... sensitize red blood ... hemolytic #anemia #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... UIP, NSIP): • Lymphocytic ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Granulomatous lymphocytic ... hemolytic anemia) • Systemic ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... : Goals: Treating ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... platelets - WBC ... number of sites of disease ... classification #hematology ... #oncology #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... : • Complete blood ... count (CBC) • ... #Rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
mesothelioma, etc - Autoimmune ... in LNs and the systemic ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... Urinary antigen testing ... count (mainly lymphocytes ... ) #Mycoses #InfectiousDiseases ... Fungal #Diagnosis #Management
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