5 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... uremic syndrome ... #Causes #differential ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... , autoimmune disorder ... Diagnosis: • hemolytic ... younger pts) Differential ... #anemia #hematology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... OnePager Summary Autoimmune ... Pulmonary Renal Syndromes ... or serologies + symptoms ... Pulmonary #Renal #Syndromes
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... changes (POEMS syndrome ... Include: • Viral infections ... Cirrhosis, ETOH, autoimmune ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... Antisynthetase syndrome ... lymphoma Overlap Syndrome ... ANTI-SYNTHETASE SYNDROME ... paraneoplastic syndrome