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anemia classification vasculitis agglutinin algorithm cold hemolysis intravascular leukemia lupus lymphocytic lymphoma management mds myelodysplasia myelodysplastic myopathy myositis syndromes vasculitides
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) (e.g. lupus, CLL ... #Causes #differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoma SLL ... with no early symptoms ... cells can indicate disease ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... rheumatologic diseases ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... #Diagnosis #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... Blood smear - RBC ... pts) Differential ... #hematology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... Lymphoma Workup ... platelets - WBC ... classification #hematology ... #oncology #management
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... frequently affected systems ... Better call hematology ... normal/high - Chronic ... #workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Diagnosis: Systemic ... Symptoms (Sx) in ... vasculitis, and SLE ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... , such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... tract, and often causes ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
• Conduction system ... inflammation • Extramuscular ... statins - probably caused ... : • PBC, autoimmune ... Myositis #Myopathy #rheumatology
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