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hematology differential management pruritus secondary anemia chronic cll common cvid hypogammaglobulinemia immunodeficiency leukemia leukostasis lymphocytic lysis macrocytic macrocytosis oncology primary
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Myelodysplastic Syndromes ... Cells, Normal WBCs ... #Macrocytosis #elevatedMCV ... #Algorithm #Causes ... #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Algorithm - Systemic ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Hyperthyroidism CBC ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #generalized #dermatology ... #Algorithm #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
noninfectious complications ... hemolytic anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Physical Exam/Signs ... Lymphocytosis on CBC ... ’s CLL Scoring system ... workup #oncology #hematology
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