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hematology management alkaline alp biliary cirrhosis differential elevation essential leukostasis lysis phosphatase polycythemiavera primary pv summary syndrome thrombocythemia tls treatment
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... intralobular bile ducts causes ... Signs and Symptoms ... #cholangitis #diagnosis ... #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... Intestine - Other causes ... Primary biliary Cholangitis ... (PBC) - Other ... #Algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... >100k, + lab signs ... Syndrome #TLS #diagnosis
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
incidentally via CBC ... , signs, and complications ... (same as ET), Thrombosis ... Treatment: • As with ET ... • Treatment algorithms
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... : On the CBC, ... RBCs & WBCs are ... • Treatment algorithms ... #hematology #diagnosis
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