9 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... PT, aPTT(liver disease ... #Diagnosis #Causes ... #Workup #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... Von Willebrand Disease ... considered first-line testing ... #disorders #hematology ... #differential #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... with or without platelet ... membrane disorder ... #Algorithm #workup ... #hematology #testing
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Proximal limb muscle wasting ... Diagnosis: • ... #cholangitis #diagnosis ... #workup #hepatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
primary biliary cholangitis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing ... #workup
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... , erythema and WBC ... • Is there a pattern ... Mechanical/degenerative disorders ... #MSK #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... metabolic or endocrine disorders ... (to support a diagnosis ... #diagnosis #testing ... #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma Workup ... - Low Hb and platelets ... - WBC may be ... #hematology #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Myeloproliferative Disease ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology