8 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... : • T lymphocyte ... Endocrinopathy, Lymphoma ... #cholangitis #diagnosis ... #workup #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... cells can indicate disease ... increase in gamma globulins ... #workup #oncology ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
decreased PLT count: CBC ... smear, HIV/HCV testing ... ), HBsAg/anti-HBc ... unclear, or if a primary ... #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
pericarditis • Hepatic: PBC ... (primary biliary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full ... platelets - WBC ... number of sites of disease ... #diagnosis #classification ... #hematology #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... - Monoclonal - Lymphoid ... Positive Coombs testing ... Blood smear - RBC ... #hematology #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... autoimmune hepatitis, PBC ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Differential Diagnosis ... the context of primary ... titers > 1:80 • CBC ... #Rheumatology