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diagnosis algorithm hematology oncology pruritus systemic classification leukemia mds myelodysplasia myelodysplastic petechiae physicalexam polycythemia primary rash rheumatology syndromes vasculitides vasculitis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... Diagnosis Secondary ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... in primary or secondary ... lesions • Severe pain ... deficiency Work ... Skin biopsy • Abdominal
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
basophilia, and thrombocytosis ... , weight loss, abdominal ... Significant ↓ PLT: Petechiae ... • Tumor lysis syndrome ... bone marrow and secondary
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... else is driving RBC ... normal/high - Chronic ... you’ll do a good workup ... #Polycythemia #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... by bleeding (petechiae ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... blood count with differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... tract, and often causes ... - GI tract: abdominal ... Supply gut -> abdominal ... Lab Tests: • CBC
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