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diagnosis hematology algorithm rheumatology oncology pruritus vasculitis allergy autoimmune classification eosinophilia leukemia mds myelodysplasia myelodysplastic myopathy myositis naildisorders petechiae petechial
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... Diagnosis Secondary ... Myelodysplastic syndrome ... #hematology #secondary
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #systemic #generalized ... #dermatology #Differential
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
discoloration) • Chronic ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm #causes
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
- DRESS - AIN ... Lymphomas - Systemic ... Hypereosinophilic Syndrome ... - Chronic Eosinophilic ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... basophilia, and thrombocytosis ... , weight loss, abdominal ... • Tumor lysis syndrome ... bone marrow and secondary
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... frequently affected systems ... else is driving RBC ... normal/high - Chronic ... you’ll do a good workup
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... into a 4-pass system ... 2nd pass = Chronic ... cell activation syndrome ... #Diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
in primary or secondary ... lesions • Severe pain ... deficiency Work ... Skin biopsy • Abdominal ... #dermatology #physicalexam
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... tract, and often causes ... - GI tract: abdominal ... Supply gut -> abdominal ... Lab Tests: • CBC
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