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diagnosis causes anemia hematology amenorrhea agglutinin cold discharge disease elevatedmcv extravascular hemolysis intravascular macrocytic macrocytosis primary secondary testing vaginal workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... uremic syndrome ... lymphoproliferative disorders ... • Intrinsic RBC ... Extravascular #Causes #differential
Causes of Vaginal Discharge - Differential Diagnosis Algorithm Neoplastic: • Endometrium • Cervix • Vulva • Vagina Systemic
Diagnosis Algorithm ... vascular disease • Dermatologic ... vaginalis Toxic Shock Syndrome ... #Causes #Gynecology ... #OBGyn
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... membrane disorder ... #Anemia #Differential ... #workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm No onset of menarche by age 16 with secondary
Primary Amenorrhea - Differential ... Diagnosis Algorithm ... Functional (e.g. eating disorder ... #Causes #OBGyn ... #Gynecology
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm Absence of menses for more than 3 cycles or
Secondary Amenorrhea - Differential ... Diagnosis Algorithm ... Functional (e.g. eating disorder ... #Causes #OBGyn ... #Gynecology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... Blood smear - RBC ... younger pts) Differential ... #anemia #hematology
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