4 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Syndrome (CAS): ... Viral Infection Clinical ... Blood smear - RBC ... younger pts) Differential ... hemolytic #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... . primary cold agglutin ... lymphoproliferative disorders ... #diagnosis #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... glucocorticoid • SAPHO syndrome ... retinoid • SAPHO syndrome ... #SAPHO #Syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
papulosquamous lesions ... dermatomyositis, Sjogren syndrome ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome