12 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... renal failure/uremia ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... #primary #secondary
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... /Liver failure ... asymptomatic • Pruritus ... #diagnosis #workup ... #hepatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... renal failure/uremia ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... #secondary #systemic
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... - Hemolytic anemia ... deficiency • Liver ... Differential #Diagnosis #hematology ... #rheumatology #
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... (ABC) analysis ... with or without cirrhosis ... hepatopulmonary #syndrome ... #treatment #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... with leukopenia, anemia ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... disease: Cirrhosis ... gastric tumors • Hematology ... differential #diagnosis #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... disease • Liver ... autoimmune hemolytic anemia ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Pruritis ... Hodgkin Lymphoma Workup ... platelets - WBC ... classification #hematology ... #oncology #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... sweats, bleeding • Pruritis ... - infiltrates (anemia ... bone marrow and secondary ... #Leukemia #Hematology