7 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
5) Symptoms of anemia ... marrow failure with anemia ... fludarabine) 3) Monoclonal ... #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... • Neutropenia, anemia ... • Richter’s Syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... Blood smear - RBC ... gammopathy of undetermined ... #hematology #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... +Organomegaly+↑RBC ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Causes of Monoclonal ... changes (POEMS syndrome ... autoimmune hepatitis, PBC ... Thalassemia, Sickle cell anemia
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Workup ... platelets - WBC ... #oncology #management
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
tissue composed of monoclonal ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology