10 results
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... , Apixaban, Dabigatran ... , Rivaroxaban ... #Anticoagulant ... #Table #Pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
e.g. warfarin) for ... : A new oral anticoagulant ... #Pharmacology #Pathophysiology ... #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... clotting #INR #heparin ... #LMWH #NOAC #warfarin ... #Xarelto #apixaban
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Anticoagulant Agents ... Warfarin - 100% ... Hepatic, 0% Renal Apixaban ... #Pharmacology # ... #anticoagulation
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... PCC (Kcentra) - Heparin ... (Praxbind) - Apixaban ... #doac #noac #pharmacology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Molecular Weight Heparin ... Enoxaparin - Warfarin ... , rivaroxaban - ... #pharmacology # ... medications #doac
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... Quick tip: apixaban ... Rivaroxaban is < ... Table
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
For patients on warfarin ... direct acting oral ... table ... inhibitor) • Apixaban ... #pharmacology #
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Xa inhibitors - Rivaroxaban ... , apixaban, edoxaban ... - Other anticoagulants ... Prolonged #Causes #diagnosis ... #differential #
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
: • Initial heparin ... typically needed • DOACs ... Xa inhibitors (rivaroxaban ... , apixaban, edoxaban ... Fibrillation #AFib #diagnosis