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classification reactions vasculitis activation cold erythematosus hemolytic hodgkins lupus lymphoma macrophage mas myopathy myositis oncology sle systemic transfusion transfusions vasculitides
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Syndrome (CAS): ... pts) Differential ... Symptoms: High fevers ... chills, flank pain ... #anemia #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... rheumatologic diseases ... fibromyalgia) • Infections ... pain • Swan neck ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... SLE], AOSD) • Infection ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... pain, dark urine ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... mucositis - Rash ... to exclude are infections ... Large Vessel: Blood ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulses, bruits, or blood ... tract: Abdominal pain ... , mucositis • Rash ... Palpable purpura, joint ... #Diagnosis #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine ... maculopapular rash ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Dyspnea • Fever ... • Pain in LN ... genes and gene products ... classification #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tenderness → Consider infectious ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... : Fever, joint pain ... Myositis #Myopathy #rheumatology
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