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rheumatology dermatology blood product reactions vasculitis dress erythematosus globulin hiv infectiousdiseases lesions leukemia lupus mycobacteria nonpalpable nontuberculous ntm oncology palpable
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... deficiency • Liver ... - APLS • Acute ... #Diagnosis #hematology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential ... Generalized itchy rash ... Pustules + Fever ... Acute generalized ... #Diagnosis #Dermatology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Syndrome Acute ... Headache (45%) • Fever ... sweats (28%) • Skin ... rash (48%) • ... enzymes ↑ • Mild anemia
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... Fever >38.5 2. ... Resolution > 15 days Differentials ... • SJS/TEN • Acute ... #dermatology #diagnosis
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... (elevations of liver ... Bone Marrow - Anemia ... #differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Disease Classification ... permanent alopecia Differential ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... to exclude are infections ... #diagnosis #rheumatology ... #classification
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... changes (POEMS syndrome ... Include: • Viral infections ... Sarcoidosis) • Liver ... #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , mucositis • Rash ... MPO > PR3 60/ GPA ... tract, and often causes ... #Diagnosis #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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