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dermatology activation chronic classification cll erythematosus joint leukemia lymphocytic macrophage mas mds myelodysplasia myelodysplastic nonpalpable pain palpable purpura rashes syndromes
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... deficiency • Liver ... #Diagnosis #hematology ... #rheumatology #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... fibromyalgia) • Infections ... lymphopenia, low PLT • Anemia ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... ], AOSD) • Infection ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... such as systemic lupus ... to exclude are infections ... vasculitis, and SLE ... #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... • Aplastic Anemia ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
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