6 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... thrombocytopenia • Liver ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... PLT: Petechiae, bruising ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Anticoagulants (Warfarin ... deficiency • Liver ... #Diagnosis #hematology ... #rheumatology #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... gingivitis or gingival leukemic ... von Willebrand syndrome ... disease • Warfarin ... Diagnosis #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Chronic B-cell activation ... Hodgkin lymphoma and leukemia ... #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... just beneath the skin ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology